Essento Labs
Preparing your analysis…
Essento Labs
Preparing your analysis…
Chromatonic simulates separations, solves pharmacopeial monographs and fits Tanaka-characterised columns - so your scientists run fewer trials, burn no solvent, and reach a validated method faster.
Paracetamol elutes at 4.82 min with Rs 4.81. Baseline separation is met; hold organic at 45% to preserve the critical pair.
Tanaka Column Fit
Monograph in, validated separation out - retrieval, column fit, simulation and gradient design in a single pass.
Essento Labs builds intelligent software for chromatography. Our work is a complete virtual HPLC laboratory where scientists design, simulate, optimise and validate methods digitally - cutting development time, cost and instrument load.
Chromatonic is a digital laboratory where chromatographers run virtual experiments before committing to physical ones. It pairs molecular data and chromatographic models with method intelligence to predict analytical outcomes, recommend conditions, and simulate separation behaviour with precision.
Every prediction is traceable to the monograph passages, column characterisation data and physicochemical descriptors that produced it - so a result can be defended in review, not just accepted.
Think of it as an experienced chromatography scientist on call around the clock, guiding method development at the bench.
Evaluate mobile phases, buffers and columns without touching an instrument.
Wet-lab iterations and solvent consumption drop as screening moves in silico.
Troubleshooting and resolution guidance whenever the lab is running.
Monograph retrieval, impurity profiles and compendial limits on demand.
Chromatonic™ covers the full method lifecycle - from structure to simulation to transfer - with each step traceable back to its evidence.
Conventional development leans on repeated laboratory trials that consume time, solvent and column life. Chromatonic moves that iteration into a virtual environment, so physical runs confirm a decision instead of searching for one.
Wet-lab runs
Screen separations virtually first, so wet-lab injections are confirmatory rather than exploratory.
Solvent use
Cut acetonitrile, methanol, buffer reagent and column-lifetime costs across every development cycle.
Faster turnaround
Compress turnaround from weeks to minutes with AI-assisted mobile phase and gradient optimisation.
Design space
Perturb pH ±0.2, temperature ±5 °C and organic ±2 % to map a defensible QbD design space.
Analyst throughput
Free analysts to handle higher sample throughput and harder impurity separations.
Prediction accuracy
Back stationary-phase and buffer choices with Tanaka selectivity data and molecular descriptors.
Chromatonic™ is built for organisations and analytical professionals working under real compliance pressure, where speed cannot come at the cost of defensibility.
Accelerate formulation release and monograph validation.
Deliver faster method development turnarounds for sponsors.
Hold batch-release methods to spec with reproducible peak shape.
Resolve complex degradation and impurity profiles.
Train analytical scientists on simulated instrumentation.
Streamline daily chromatographic workflows with AI support.
Diagnose tailing, fronting and pressure anomalies quickly.
Document QbD robustness for ICH and FDA submissions.
Chromatonic™ · Simulate. Optimise. Innovate.